Library / English Dictionary

    TOXICITY

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Grave harmfulness or deadlinessplay

    Synonyms:

    perniciousness; toxicity

    Classified under:

    Nouns denoting attributes of people and objects

    Hypernyms ("toxicity" is a kind of...):

    morbidity; morbidness; unwholesomeness (the quality of being unhealthful and generally bad for you)

    Sense 2

    Meaning:

    The degree to which something is poisonousplay

    Classified under:

    Nouns denoting quantities and units of measure

    Hypernyms ("toxicity" is a kind of...):

    definite quantity (a specific measure of amount)

    Hyponyms (each of the following is a kind of "toxicity"):

    cytotoxicity (the degree to which something is toxic to living cells)

    Derivation:

    toxic (of or relating to or caused by a toxin or poison)

    Credits

     Context examples: 

    Pegylation provides improved drug penetration into tumors and decreases drug clearance, thereby increasing the duration of therapeutic effects while lowering the toxicity profile.

    (Pegylated Irinotecan, NCI Thesaurus)

    A toxicity study that assesses potential harm to the immune system.

    (Other Toxicity Studies: Immunotoxicity, NCI Thesaurus/CDISC)

    This decreases activated 5-FU-related gastrointestinal toxicity.

    (Oteracil, NCI Thesaurus)

    The potassium salt of oxonate, an enzyme inhibitor that modulates 5- fluorouracil (5-FU) toxicity.

    (Oteracil Potassium, NCI Thesaurus)

    A pyrimidinedione-based diuretic and isomer of aminometradine with less toxicity.

    (Amisometradine, NCI Thesaurus)

    Upon intravenous administration, autologous CD19-28z CAR-expressing T-lymphocytes are directed to CD19-expressing tumor cells, which induces selective toxicity in CD19-expressing tumor cells.

    (Autologous CD19-28z Chimeric Antigen Receptor-expressing T-lymphocytes, NCI Thesaurus)

    Chemical manufacturers conducted some toxicity studies on the compounds during this period, but they were never published.

    (Common Household Chemicals Lead to Birth Defects in Mice, The Titi Tudorancea Bulletin)

    Concern has often focused on the toxicity or carcinogenic properties of the metals, particularly at high doses.

    (Experts warn of cardiovascular risk from heavy metal pollution, University of Cambridge)

    URI protects these cells from high-dose radiation-induced toxicity.

    (New Way Discovered for Protecting against High-Dose Radiation Damage, The Titi Tudorancea Bulletin)

    To measure the peptides' toxicity, the researchers exposed them to human embryonic kidney cells grown in a lab dish.

    (Venom of Wasp, Bee Repurposed as Antibiotic Drug, The Titi Tudorancea Bulletin)


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